Influence of cell cycle on the imprinting
Mean growth rates of Tetrahymena pre-exposed to T2 in different
phases of cell cycle
Beginning of imprinting |
Duration of imprinting |
Mean |
G1 |
4 h |
19.1 |
After 100 min (S) |
4 h |
16.0 |
G1 |
15’ |
20.6 |
After 100 min (S) |
15’ |
16.4 |
After 140 min (G2) |
15’ |
15.0 |
Without treatment at all |
|
13.2 |
Without pretreatment |
|
14.2 |
Significances: p<0.01 to
control (without treatment at all); p<0.01 between G1 and
S and between G1 and G2. T2=diiodotyrosine
Conclusions:
1.The intensity of hormonal imprinting depends on the phase of cell cycle,
2.The effect of imprinting is greater in the
case of G1 than in S or G2.