Table 1.
Effect of signal molecules (hormones) on the phagocytosis of protozoa (Tetrahymena
pyriformis)
|
Signal |
Effect |
Effective
domain |
Peak |
Reference |
|
Histamine |
stimulation |
10-7
– 10-11 |
10-9 |
Csaba,
G., Lantos, T. Cytobiologie 7: 361-365, 1973 |
|
Serotonin |
stimulation |
10-7
– 5x10-9 |
10-8 |
as
above |
|
Indole
acetic acid |
---- |
----- |
---- |
as
above |
|
Histamine
an- tagonist,chlo-ropyramine |
stimulation |
10-6
– 10-12 |
10-9 |
Csaba,
G., Lantos, T. Cytobiologie 11:
44-49,1975 |
|
Histamine
an-tagonist, phenergan |
stimulation |
10-7
– 10-11 |
10-9 |
as
above |
|
Serotonin
an-tagonist,meth- oxytryptamine |
stimulation |
10-8
– 10-9 |
10-8 |
as
above* |
|
Adrenalin |
stimulation |
10-5
– 10-9 |
10-7 |
Csaba,
G., Lantos, T. Acta Protozool. 13: 409-413, 1975 |
|
Insulin |
stimulation |
10-9
– 10-10 |
10-10 |
as
above |
|
Thyroxin |
stimulation |
10-9
– 10-12 |
10-11 |
as
above |
*serotonin
antagonists, tryptamine, methoxytryptamine and gramine inhibited the
phagocytosis stimulating activity of serotonin given before, differently,
depending on the structure of the molecule.
Conclusions: