Table 8

 

Binding and internalization of epinephrine in Tetrahymena. Quantitative autoradiographic study.

 

(Csaba, G., Sudár, F., Pados, R., Endokrinologie 76, 340-344, 1980).

 

 

Group

Grains/cell

3H-epinephrine

12.7

Epinephrine pretreatment before 3H-e

2.6

Epinephrine posttreatment after 3H-e

4.1

 

Signficance to control: p<0.01

 

 

Conclusions:

 

  1. Epinephrine is specifically bound by Tetrahymena. .
  2. Epinephrine appears on the cell membrane, in cytoplasmic vacuoles and nucleus.
  3. Most of the epinephrine is on the cell membrane (cilia) and only traces enter to the nucleus, where the localization is always heterochromatic.