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xCELLigence SP system

Description

Biological parameters screened: - cell adhesion

                                                     - proliferation/cytotoxicity

                                                     - barrier function

Rapid measurement time - less than 10 or 60 seconds

Frequencies: 10, 25, 50 kHz

HTS technology - 96 wells (E-plate)

RTCA 1.2 software calculates:

        Cell Index    CI_i = (R_tn - R_to) / F_i

        Delta Cell Index

        Normalized Cell Index

        IC₅₀ and EC₅₀

Curve repair function