Chemotaxis Research Group

Department of Genetics, Cell and Immunobiology

Semmelweis University

Nagyvárad tér 4., Budapest, Hungary 1089

 

News

   IBCA 2023


    Program

 


 

Recent publications (2011-2023):

2023

Kiss LZs,  Nyárády BB, Pállinger É, Lux Á, Jermendy ÁL,  Csobay‑Novák Cs, Soós ·P, Szelid Zs, Láng O, Kőhidai L, Dinya E, ·Dósa E, Merkely B, Bagyura Zs. Association of growth and diferentiation factor‑15 with coronary artery calcium score and ankle‑brachial index in a middle‑aged and elderly Caucasian population sample free of manifest cardiovascular disease. GeroScience doi: 10.1007/s11357-023-00899-y (2023)

Bagyura Zs, Kiss L, Lux Á, Csobay-Novák Cs, Jermendy ÁL, Polgár L, Tabák Á, Soós P, Szelid Zs, Merkely B, Kőhidai L, Pállinger É. Neutrophil/lymphocyte ratio is an independent risk factor for coronary artery disease in central obesity. International Journal of Molecular Sciences, Special Issue "The Role and Characterization of Neutrophils in Human Diseases. Int. J. Mol. Sci.  24, 7397. doi: 10.3390/ ijms24087397 (2023)

Matyas Cs, Trojnar E, Zhao S, Arif M, Mukhopadhyay P, Kovacs A, Fabian A, Tokodi M, Bagyura Zs,  Merkely B, Kohidai L, Lajko E, Takacs A, He Y, Gao B, Paloczi J, Lohoff FW, Haskó Gy, Ding W-X,  Pacher P. PCSK9, a promising novel target for age-related cardiovascular dysfunction. JACC Basic to Translation Science  (in press)

Tóth K, Fekete N, SimonVK, Tóth B, Kovács ÁF, Pállinger É, Antal I, Kőhidai L, Jedlovszky-Hajdú A , Juriga D, S.  Nagy K. Different implantable electrospun meshes for simultaneous application of prednisone and doxorubicin. J. Mol. Liquids doi: 10.1016/j.molliq.2023.121854 (2023)

 

2022

Kőhidai Zs, Takács A, Lajkó E, Géczi Z, Pállinger É, Láng O, Kőhidai L The effects of mouthwashes in human gingiva epithelial progenitor (HGEPp) cells. Clin. Oral Invest. doi:10.1007/s00784-022-04422-z

Kalabay M, Szász Zs, Láng O, Lajkó E, Pállinger É, Duró C, Jernei T, Csámpai A, Takács A, Kőhidai L Investigation of the antitumor effects of tamoxifen and its ferrocene-linked derivatives on pancreatic and breast cancer cell lines. Pharmaceuticals doi:10.3390/ph15030314

Géczi Z, Róth I, Kőhidai Z, Kőhidai L, Mukaddam K, Hermann P, Végh D, Zelles T. The use of Trojan-horse drug delivery system in managing periodontitis. Int Dent J. doi: 10.1016/j.identj.2022.08.003.

2021

     Khorolsuren Z, Láng O, Vág J, Kőhidai L. Effect of dental antiseptic agents on the viability of human periodontal ligament cells. The Saudi Dental Journal 33, (8): 904-911 (2021) doi: 10.1016/j.sdentj.2021.09.016

      S. Nagy K, Toth K, Pállinger E, Takács A, Kőhidai L, Jedlovszky-Hajdu A, Máthé D, Kovács N, Veres DS, Szigeti K, Molnár K, Krisch E, Puskás JE. Folate-targeted Monodisperse PEG-based Conjugates made by Chemo-enzymatic Methods for Cancer Diagnosis and Treatment. Intnl Journal Mol Sci (2021)  doi:10.3390/ijms221910347

     Bagyura Z, Takács A, Kiss L, Dósa E, Vadas R, Nguyen TD, Soós P, Szelid Zs, Kőhidai L, Merkely B. Level of advanced oxidation protein products is associated with subclinical atherosclerosis. BMC Cardiovasc Disord 22, 5 (2022)

    Takács A, Szász Z, Kalabay M, Bárány P, Csámpai A, Hegyesi H, Láng O, Lajkó E, Kőhidai L. The Synergistic Activity of Bortezomib and TIC10 against A2058 Melanoma Cells. Pharmaceuticals (Basel) 2021, 14(8):820. doi: 10.3390/ph14080820

     Barczikai D, Domokos J, Szabó D, Molnar K, Juriga D, Krisch E, Nagy KS, Kohidai L, Helfer CA, Jedlovszky-Hajdu A, Puskas JE. Polyisobutylene—New Opportunities for Medical Applications. Molecules 2021, 26:5207. doi:10.3390/molecules26175207

    Díaz López E, Ríos Díaz A, Vanegas Calderón O, Lajkó E, Ponte-Sucre A, Kőhidai L. Chemotaxis in Leishmania (Viannia) braziliensis: Evaluation by the two-chamber capillary assay. MethodsX doi:10.1016/j.mex.2021.101223

    2020

    Lang O, Nagy K, Lang J, Perczel-Kovach K, Herczegh A, Lohinai Zs, Varga G, Kohidai L. Comparative study of hyperpure chlorine dioxide with two other irrigants regarding the viability of periodontal ligament stem cells. Clin. Oral Inv. doi:10.1007/s00784-020-03618-5

     Pethő L, Kasza Gy, Lajkó E, Láng O, Kőhidai L, Iván B, Mező G. Amphiphilic drug-peptide-polymer conjugates based on poly(ethylene glycol) and hyperbranched polyglycerol for epidermal growth factor receptor targeting: the effect of the conjugate aggregation on the in vitro activity. Soft Matter 16, 5759-5769 (2020) doi:10.1039/d0sm00428f /2020/

    Takács A, Lajkó E, Láng O, Istenes I, Kőhidai L. Alpha-lipoic acid alters the antitumor effect of bortezomib in melanoma cells in vitro. Scientific Rep. 10(1):14287. doi: 10.1038/s41598-020-71138-z. /2020/

2019

Lajkó E, Pállinger É, Kovács Zs, Szabó I, Kőhidai L. Effects of gonadotropin-releasing hormone (GnRH) and its analogues on the physiological behaviors and hormone content of Tetrahymena pyriformis. Int J Mol Sci 20: 5711; DOI:10.3390/ijms20225711 /2019/

Jernei T, Duró C, Dembo A, Lajkó E, Takács A, Kőhidai L, Schlosser G, Csámpai A. Synthesis, structure and in vitro cytotoxic activity of novel cinchona-chalcone hybrids with 1,4-disubstituted- and 1,5-disubstituted 1,2,3-triazole linkers. Molecules 24: 4077; DOI:10.3390/molecules24224077 /2019/

Hegyesi H, Sándor N, Sáfrány G, Lovas V, Kovács Á, Takács A, Kőhidai L, Turiák L, Kittel Á, Pálóczi K, Bertók L, Buzás EI. Radio-detoxified LPS alters bone marrow-derived extracellular vesicles and endothelial progenitor cells.  Stem Cell Res Ther. 10(1):313. DOI: 10.1186/s13287-019-1417-4. /2019/

Lajkó E, Hegedűs R, Mező G, Kőhidai L Apoptotic effects of drug targeting conjugates containing different GnRH analogs on colon carcinoma cells. Int J Mol Sci. DOI: 10.3390/ijms20184421. /2019/

Lang O, Kohidai L, Kohidai Z, Dobo-Nagy C, Csomo KB, Lajko M, Mozes M, Keki S, Deak G, Tian KV, Gresz V. Cell physiological effects of glass ionomer cements on fibroblast cells. Toxicol In Vitro. DOI: 10.1016/j.tiv.2019.104627. /2019/

Kovács ÁF, Fekete N, Turiák L, Ács A, Kőhidai L, Buzás EI, Pállinger É Unravelling the role of trophoblastic-derived extracellular vesicles in regulatory T cell differentiation. Int J Mol Sci. DOI: 10.3390/ijms20143457 /2019/

Fazekas R, Molnár B, Kőhidai L, Láng O, Molnár E, Gánti B, Michailovits G, 
Windisch P, Vág J. Blood flow kinetics of a xenogeneic collagen matrix following 
a vestibuloplasty procedure in the human gingiva - An explorative study. Oral
Dis. DOI: 10.1111/odi.13163 /2019/

Mező G, Dókus L, Schlosser G, Lajkó E, Szász Zs, Randelovic I, Biri-Kovács B,
Tóvári J, Kőhidai L. Hasnyálmirigytumort célzó terápiás irányítópeptidek összehasonlítása.
Magyar Onkológia 63: 301-308 /2019/

 

2018

Tziakouri A, Lajkó E and Kőhidai L The phylogenetic background of neurotransmitters in the unicellular organism Tetrahymena pyriformis.  Annal. Behav. Neurosci. 1 108-118 DOI:10.18314/abne.v1i1.1229 /2018/.

Géczi Z, Hermann P, Kőhidai L, Láng O, Kőhidai Zs, Mészaros T, Barocsi A, Lenk S, Zelles T. Antimicrobial silver-polyethyleneimine-polylactic acid polymer composite film for coating methacrylate-based denture surfaces.  J Nanomater DOI: 10.1155/2018/1048734 /2018/ 

Lajkó E, Spring S, Hegedüs R, Biri-Kovács B, Ingebrandt S, Mező G, Kőhidai L. Comparative cell biological study of in vitro antitumor and antimetastatic activity on melanoma cells of GnRH-III-containing conjugates modified with short-chain fatty acids. Beilstein J. Org. Chem. 14: 2495–2509 /2018/        Supp mat 1 Supp mat 2

Bárány P, Oláh R, Kovács I, Czuczi T, Szabó CSL, Takács A, Lajkó E, Láng O, Kőhidai L,  Schlosser G, Bősze Sz, Mező G, Hudecz F, Csámpai A. Ferrocene-containing impiridone (ONC201) hybrids: synthesis, DFT modelling, in vitro evaluation and structure-activity relationships. Molecules 23:9 pii: E2248. DOI: 10.3390/molecules23092248

Polgár L, Lajkó E, Soós P, Láng O, Manea M, Merkely B, Mező G, Kőhidai L. Drug targeting to decrease cardiotoxicity – Determination of the cytotoxic effect of GnRH-based conjugates containing doxorubicin, daunorubicin and methotrexate on human cardiomyocytes and endothelial cells. Beilstein J. Org. Chem. 14: 1583-1594 /2018/ Supp mat 1    Supp mat 2

Nagy K, Láng O, Láng J, Perczel-Kovách K, Gyulai-Gaál Sz, Kádár K, Kőhidai L, Varga G.  A novel hydrogel scaffold for periodontal ligament stem cells. Interv. Med. Appl. Sci. 10: 162-170 /2018/

Varjú I, Farkas VJ, Kőhidai L, Szabó L, Farkas ÁZ, Polgár L, Chinopoulos Ch,  Kolev K. Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin. Sci. Rep. 8: 5366  DOI:10.1038/s41598-018-23725-4  /2018/

Kovács ÁF, Láng O, Turiák L, Ács A, Kőhidai L, Fekete N, Aszlatics B, Mészáros T,  Buzás E, Rigo Jr J, Pallinger É. The impact of circulating preeclampsia-associated extracellular vesicles on the migratory activity and phenotype of THP-1 monocytic cells. Sci. Rep.  8: 5426 DOI:10.1038/s41598-018-23706-7 /2018/

Baricza E, Marton N, Királyhidi P, Kovács OT, Kovacsné Székely I, Lajkó E, Kohidai L, Rojkovich B, Érsek B, Buzás E, Nagy Gy. Distinct in vitro Th17 differentiation capacity of peripheral naive T cells in rheumatoid and psoriatic arthritis. Front. Immunol.  9: 606 DOI: 10.3389/fimmu.2018.00606

Polgár L, Soós P, Lajkó E, Láng O, Merkely B, Kőhidai L. Platelet impedance adhesiometry - A novel technique for the measurement of platelet adhesion and spreading. Int. J. Lab. Hemat. 40: 372-381 /2018/ DOI: 10.1111/ijlh.12799.

Lajkó E, Tuka B, Fülöp F, Krizbai I, Toldi J, Magyar K, Vécsei L, Kőhidai L. Kynurenic acid and its derivatives are able to modulate the adhesion and locomotion of brain endothelial cells. J Neural Transm (Vienna). 125: 899-912 /2018/ DOI: 10.1007/s00702-018-1839-7.

2017

Gibbons A, Lang O, Kojima Y, Ito M, Ono K, Tanaka K, Sivaniah E. Real-time visualization of cardiac cell beating behaviour on polymer diffraction gratings. RSCAdv. 7:51121–51129 /2017/

Láng O, Kőhidai L, Wegener J Label-free pro filing of cell dynamics: A sequence of impedance-based assays to estimate tumor cell invasiveness in vitro. Exp Cell Res. (DOI: 10.1016/j.yexcr.2017.07.023)

Bäcker H, Polgár L, Soós P, Lajkó E, Láng O, Merkely B, Szabó G, Dohmen PM, Weymann A, Kőhidai L. Impedimetric analysis of the effect of decellularized porcine heart scaffold on human fibrosarcoma, endothelial, and cardiomyocyte cell lines. Med Sci Monitor 23: 2232-2240 /2017/

Sebestyén M, Szabó R, Kőhidai L, Pállinger É, Mező G, Kóczán Gy, Hudecz F. Synthesis, conformation and cytotoxicity of new, branched polymeric polypeptides containing hydrophobic amino acid or arginine moiety. Struct Chem. 28: 527-535 /2017/

2015 - 2016

Kőhidai L. Chemotaxis as an expression of communication of Tetrahymena. In: Biocommunication of ciliates. Ed: Witzany G. Springer pp. 65-82 /2016/

Lajkó E, Bányai P, Zámbó Zs, Kursinszki L, Szőke É, Kőhidai L. Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1). Cancer Cell Internat. 15:119 /2015/

Biri B, Kiss B, Király R, Schlosser G, Láng O, Kőhidai L, Fésüs L, Nyitray L. Metastasis-associated S100A4 is a specific amine donor and an activity-independent binding partner of transglutaminase-2. Biochemical J. 473:31-42 /2016/

Kőhidai L, Tóth K, Samotik P, Ranganathan K, Láng O, Tóth M, Ruskoaho H. Effect of vasoactive peptides in Tetrahymena - Chemotactic activities of adrenomedullin, proadrenomedullin N-terminal 20 peptide (PAMP) and calcitonin gene-related peptide (CGRP). Mol. Cell. Biochem. 411:271–280 /2016/

Diaz E, Zacarias AK, Pérez S, Vanegas O, Köhidai L, Padrón-Nieves M, Ponte-Sucre A. Effect of aliphatic, monocarboxylic, dicarboxylic, heterocyclic and sulphur-containing amino acids on Leishmania spp. chemotaxis. Parasitology 23:1-10 /2015/

Szemes Á, Lajkó E, Láng O, Kőhidai L. Chemotactic effect of mono- and disaccharides on the unicellular Tetrahymena pyriformis. Carbohydrate Research 407:158-165/2015/

Enyedi KN, Czajlik A, Knapp K, Láng A, Majer Z, Lajkó E, Kőhidai L, Perczel A, Mező G. Development of Cyclic NGR Peptides with Thioether Linkage: Structure and Dynamics Determining Deamidation and Bioactivity. J Med Chem. - Epub ahead of print /2015/

Muto Y, Guindon S, Umemura T, Kőhidai L, Ueda H. Adaptive evolution of formyl Peptide receptors in mammals. J Mol Evol. 80:130-141 /2015/

Szabó, R., Láng, O., Láng, J., Illyés, E., Kőhidai, L. Hudecz, F. Effect of SXWS/WSXWS peptides on chemotaxis and adhesion of the macrophage-like cell line J774. J Mol Recogn. doi: 10.1002/jmr.2439 /2015/

2014

Kuo CH, Láng J, Láng O, Kőhidai L, Sivaniah E. The facile generation of two-dimensional stiffness maps in durotactic cell platforms through thickness projections of three-dimensional submerged topography. Methods Cell Biol. 121:49-60 /2014/

 

2013

Arany E, Láng J, Somogyvári D, Láng O, Alapi T, Ilisz I, Gajda-Schrantz K, Dombi A, Kőhidai L, Hernádi K. Vacuum ultraviolet photolysis of diclofenac and the effects of its treated aqueous solutions on the proliferation and migratory responses of Tetrahymena pyriformis.Sci Total Environ. 468-469C, 996-1006 /2013/

Díaz E, Köhidai L, Ríos A, Vanegas O, Silva A, Szabó R, Mező G, Hudecz F, Ponte-Sucre A. Leishmania braziliensis: Cytotoxic, cytostatic and chemotactic effects of poly-lysine-methotrexate-conjugates.Exp Parasitol. 135, 134-141 /2013/

 

Lajkó E, Szabó I, Andódy K, Pungor A, Mező G, Kőhidai L. Investigation on chemotactic drug targeting (chemotaxis and adhesion) inducer effect of GnRH-III derivatives in Tetrahymena and human leukemia cell line.J Pept Sci. 19, 46-58 /2013/

2012

Kőhidai, L., Lajkó, E., Pállinger, É., Csaba, G. Verification of epigenetic inheritance in a unicellular model system. Multigenerational effects of hormonal imprinting. Cell Biol. Int. 36, 951–959  /2012/

 

Lang, J., Kohidai, L. Effects of the aquatic contaminant human pharmaceuticals and their mixtures on the proliferation and migratory responses of the bioindicator freshwater ciliate Tetrahymena. Chemosphere 89,592–601 /2012/

Kohidai, L. Tetrahymena pyriformis in motion. In: Microbiorobotics - Biologically Inspired Microscale Robotic Systems. Eds. Kim, MJ, Steager, E., Agung, AJ. Elsevier, pp 55-84 /2012/ 

Leurs, U., Lajkó, E.,Mező, G., Orbán, E.,  Öhlschläger, C.P., Marquardt, A., Kőhidai, L., Manea, M. GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate. Eur. J. Med. Chem. 52, 173-183 /2012/

Láng, O., Illyés, E., Menyhárd D.K., Láng, J., Sebestyén, F., Hudecz, F., Kőhidai, L. Chemotaxis induced by SXWS tetrapeptides in Tetrahymena—overlapping chemotactic effects of SXWS sequences and their identical amino acids. J. Mol. Recogn. 25, 24-31 /2012/

Lajkó, E. Polgár, L., Lengyel, J., Láng, O., Kőhidai, L., Magyar, K. Basic cell physiological activities (cell adhesion, chemotaxis, proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes. J. Neural Transm 119, 545-556 /2012/

2011

Láng, J., Rákász, V., Magyar, A., Pállinger, É., Kőhidai, L. Chemotactic effect of odorants and tastants on the ciliate Tetrahymena pyriformis. J. Rec. Sign. Transd. 31, 423-433 /2011/

Sáfár, O., Kőhidai, L., Hegedűs, A. Time-delayed model of unibased movement of Tetrahymena pyriformis. Period. Math. Hung. 63, 215-225 /2011/

Díaz, E., Köhidai, L., Ríos, A., Vanegas, O., Ponte-Sucre, A. Chemotaxis assays in vitro in Leishmania sp. evaluation of the capillary-two chambers technique in promastigotes. Rev. Facult. Farm. 74, 31-39 /2011/

 

Book chapters:

Abdallah, M.W., Michel, T., Kohidai, L. Autism spectrum disorders and circulating chemokines. In: The Comprehensive Guide to Autism, Eds. Patel, VB, Preedy, VR., Martin, CR; Springer; pp 1627-1642 /2014/

Kőhidai L, Lajkó E, Szabó I, Polgár I, Manea M, Mező G. GnRH-based drug targeting: Cell adhesion and migration modulator effects of GnRH derivatives in tumor cells. In: Gonadotropin-releasing hormone (GnRH): Production, structure and functions. Ed. Sills ES; Nova Publ. pp. 254-272 /2013/ 

Kőhidai, L. MIGRATION OF IMMUNE COMPETENT CELLS, HOMING AND EXTRAVASATION IN INFLAMMATION. In: Seminars in Immunology. Ed. Fülöp, K.; Semmelweis University, Budapest; pp. 133-150 (2012)  ISBN 978-963-9129-82-5
 
Kőhidai, L. DIE HOMING, DIE GEZIELTE MIGRATION VON IMMUNZELLEN. EXTRAVASATION IN ENTZÜNDUNGEN. Immunologie Seminare. Ed. Pap, E.; Semmelweis Universität, Budapest; pp. 148-162 (2012)  ISBN 978-963-9129-83-2

Kőhidai, L. AZ IMMUNSEJTEK MIGRÁCIÓJA, HOMING ÉS GYULLADÁSOS EXTRAVAZÁCIÓ. In: Immunológiai szemináriumok. Ed. Fülöp, K.;Semmelweis Egyetem, Budapest; pp. 130-148 (2012) ISBN 978-963-9129-81-8

 

Recent oral presentations:

    Kőhidai L, Lajkó E, Dókus L, Láng O, Jernei T, Takács A, Bárány P, Enyedi KN, Németh Zs, Csámpai A, Pállinger É, Mező G. Impedance-based analysis as a dedicated technique to characterize efficacy of novel antitumour compounds. (4th Conference on Impedance-Based Cellular Assays - IBCA2018, Edinburgh, 2018)

    Khorulsuren Z, Lang O, Pallinger E, Foldes A, Horváti K, Mezo G, Vag J, Kohidai L. Effects of novel synthetic polypeptides containing ‘cycloRGD’ sequences – on PDLSC functional characterization. (Chemotaxis Workshop 2017, Budapest, 2017)

    Khorolsuren, Z., Lang, O., Pallinger, E., Foldes, A., Horváti, K., Mezo, G., Vag, J., Kohidai, L Effects of novel synthetic polypeptides containing ‘cycloRGD’ sequences - on PDLSC functional characterization. (PhD Scientific Meeting 2017, Budapest, 2017)

    Láng, O., Kőhidai, L. Impedimetric characterisation of cell physiological responses in oral biology. (3rd Conference on Impedance-Based Cellular Assays, Regensburg, 2016)

    Lajkó, E., Spring, S., Láng, O., Ingebrandt, S., Mező, G., Kőhidai, L. Impedance-based analysis and holographic phase imaging of the GnRH-III-based drug-targeting in melanoma cells. (3rd Conference on Impedance-Based Cellular Assays, Regensburg, 2016)

    Biri, B., Vadászi, H., Kiss, B., Ligeti, Z., Csikós, Gy., Lajkó, E., Láng, O., Kőhidai, L., Nyitray, L. Effect of extracellular S100A4 on cell adhesion and migration of epithelial carcinoma cells. (Molecules of Life, FEBS3+ Meeting, Portoroz, 2015)

    Kőhidai, L. Chemotaxome - A new member with complex biological entities in systems biology.(158th iCeMS Seminar - iCeMS - Kyoto University, Kyoto, 2014)

    Kőhidai, L. Chemotaxome – A new member with complex biological entities in systems biology. (BSS Formal Seminar, Cavendish Laboratory, University of Cambridge, 2013.)

    Kőhidai, L. ECIS Migration (ECIS Tutorial on Impedance-Based Cellular Assays, Budapest, 2013.)

    Kőhidai, L., Láng, O., Lajkó, E., Láng, J., Polgár, L., Mező, G. Impedimetry assays – Dedicated ways to evaluate migratory behavior of cells (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Láng, O., Nagy, K., Láng, J., Perczel-Kovách, K., Varga, G., Kőhidai, L. Monitoring dental stem cells on self-assembling peptide hydrogel scaffold by impedance based techniques. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Lajkó, E., Bányai, P., Zámbó, Zs., Szőke, É., Kőhidai, L. Natural cancer therapeutics – The effects of anthraquinones derived from Rubia tinctorum L. on melanoma cell lines. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Kosztin, A., Polgár, L., Kőhidai, L., Földes, G. Angiogenic effect of human pluripotent stem cell-derived endothelial cells. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Measurement of platelet function with impedimetry - The effect of agonists and heparin on adhesion and spreading of human platelets. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.

    Kőhidai, L., Lajkó, E, Láng, J., Láng, O., Vizi, T., Csaba, G., Pállinger, É. Apoptotic and anti-apoptotic effects of prenatal drugs in BeWo human trophoblast cells. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)

   

 

    Recent poster presentations:

 


 

    Lajkó, E., Magyar, K., Kőhidai, L. Real-time monitoring the endothelial reaction induced by R-deprenyl using holographic microscopy and impedance-based method. (Microscopy Conference 2017, Lausanne, Switzerland, 2017)


    Giammarresi M, Díaz E, Vanegas O, Kőhidai L, Padrón Nieves M, Ponte-Sucre A. Role of CGRP1 , NK1 and VPAC receptors on chemotactic responses induces by putative ligands in vitro on promastigotes of Leishmania (Viannia) braziliensis. (Chemotaxis Workshop 2017, Budapest, 2017)
 

    Takács, A., Lajkó, E., Istenes, I., Kőhidai, L., Láng, O. Study of the apoptotic and cell cycle modulator effects of bortezomib in combination with antioxidants in melanoma and myeloma cell lines. (Chemotaxis Workshop 2017, Budapest, 2017)
 

    Lajkó, E., Magyar, K., Kőhidai, L. Impedimetric and holographic microscopic measurements on endothelial cell reactions induced by R-deprenyl. (Chemotaxis Workshop 2017, Budapest, 2017)
 

    Khorolsuren, Z., Lang, O., Pallinger, E., Foldes, A., Vag, J., Kohidai, L. Functional characterization of PDLSC maintained on synthetic peptide coated surface. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Krausz, M., Kovács, ÁF., Kőhidai, L., Pállinger, É., Láng, O. Physiological effects of melanoma derived extracellular vesicles on immune cells. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Kőhidai, L., Hamada, M., Tziakouri, A., Lajkó, E., Horváti, K., Mező, G., Muto, Y., Láng, O. Molecular evolution of CCL2 chemokines – Chemotactic ability of 47R, 72K and 89H pentapeptide libraries of MCP-1 in Tetrahymena. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Lang, O., Debrei, D., Kőhidai, Zs., Mező, G, Kőhidai, L. Screening of tuftsin based oligopeptide library on model cells of oral cavity. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Lajkó, E., Magyar, K., Kőhidai, L. Study of the effect of R-deprenyl on endothelial function by impedimetry and holographic phase imaging. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Lajkó, E., Law, J.K-Y., Spring, S., Hempel, F., Láng, O., Mező, G., Ingebrandt, S., Kőhidai, L. Monitoring the tumor selective effects of GnRH-drug conjugates with FET- and MEA-based methods. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Takács, A., Lajkó, E., Istenes, I., Kőhidai, L., Láng, O. The molecular background of the effectiveness of bortezomib in combination with antioxidants in melanoma and myeloma cell lines. (Hungarian Molecular Life Sciences Conference 2017, Eger, 2017)
 

    Takács, A., Lajkó, E., Istenes, I., Kőhidai, L., Láng, O. Comparative study on the effectiveness of bortezomib in combination with alpha lipoic acid and thiamine in melanoma and myeloma cell lines. (3rd Conference on Impedance-Based Cellular Assays, Regensburg, 2016)
 

    Lajkó, E., Spring, S., Láng, O., Ingebrandt, S., Mező, G., Kőhidai, L. Impedance-based analysis and holographic phase imaging of the GnRH-III-based drug-targeting in melanoma cells. (3rd Conference on Impedance-Based Cellular Assays, Regensburg, 2016)
 

    Kovács, Á.F., Láng, O., Kőhidai, L., Rigó, L., Fekete, N., Buzás, E.I., Pállinger, É. Impact of preeclampsia-associated extracellular vesicles on the monocyte-macrophage system: an in vitro analysis. (ISEV 2016 Annual Meeting, Rotterdam, 2016)
 

    Láng, O., Láng, J., Sivaniah, E., Kőhidai, L. Mechanopharmacological screening platform. (Hungarian Molecular Life Sciences Conference 2015, Eger, Hungary, 2015)
 

    Láng, O., Kőhidai, Zs., Nagy, K., Láng, J., Nagy, K., Perczel-Kovách, K., Lohinai, Zs., Varga, G., Kőhidai, L. Biological effect of mouthwash compounds on dental stem cells and gingival epithelium. (Hungarian Molecular Life Sciences Conference 2015, Eger, Hungary, 2015)
 

    Biri, B., Kiss, B., Király, R., Schlosser, G., Láng, O., Kőhidai, L., Fésüs, L., Nyitray, L. Metastasis-associated S100A4 serves as a specific amine substrate for tissue transglutaminase-2. (Hungarian Molecular Life Sciences Conference 2015, Eger, Hungary, 2015)
 

    Kosztin, A., Polgár, L., Kőhidai, L., Várnai, P., Gara, E., Skopál, J., Harding, S., Merkely, B., Földes, G. Angiogenic and positive inotropic effects of apelin fragments on human pluripotein stem cell-derived cardivascular cells. (FEPS-2014, Budapest, 2014)
 

    Lajkó, E., Mércz, K., Polgár, L., Manea, M., Szabó, I., Pállinger, É., Mező, G., Kőhidai, L. Investigations on the prospective use of GnRH-III based conjugates for targeted chemotherapy as drug delivery systems in different tumor cells. (The 11th International Symposium on GnRH, Salzburg, Austria, 2014)
 

    Enyedi, K.N., Kőhidai, L., Lajkó, E., Mező, G. Targeting cancer-associated fibroblast by their tumor specific receptors. (EU COST, Chemical Approaches to Targeting Drug Resistance in Cancer Stem Cells - 2nd Working Group Meeting, Budapest, Hungary, 2014)
 

    Giammarresi, M., Vanegas, O., Díaz, E., Köhidai, L., Padrón M., Ponte-Sucre, A. Papel de los receptores NK1 en la respuesta quimiotáctica inducida in vitro por SP en promastigotes de Leishmania (Viannia) braziliensis. (V Jornadas del Postgrado de Farmacología, (sin libro de resúmenes), Universidad Central de Venezuela, Caracas, 2014.)
 

    Giammarresi, M., Vanegas, O., Díaz, E., Köhidai, L., Padrón M., Ponte-Sucre, A. Papel de los receptores NK1 en la respuesta quimiotáctica inducida in vitro por SP en promastigotes de Leishmania (Viannia) braziliensis. (LXV Convención Anual de AsoVAC. Caracas, Venezuela, 2014.)
 

    Lajkó, E., Bányai, P., Zámbó, Zs., Szőke, É., Kőhidai, L. Natural cancer therapeutics – The effects of anthraquinones derived from Rubia tinctorum L. on melanoma cell lines. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Kosztin, A., Polgár, L., Kőhidai, L., Földes, G. Angiogenic effect of human pluripotent stem cell-derived endothelial cells. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Measurement of platelet function with impedimetry - The effect of agonists and heparin on adhesion and spreading of human platelets. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Biri, B., Láng, O., Méhes, E., Czirók, A., Kőhidai, L., Nyitray, L. Motility and adhesion assays related to the effect of metastasis-associated S100A4 protein. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Láng, J., Kuo, R., Láng, O., Kőhidai, L., Sivaniah, E. Study of the interdependence of cell adhesion migration and mechanosensing using a complex, innovative approach. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Slezák, S., Lajkó, E., Pállinger, É., Bai, K.B., Mező, G., Gera, I., Kőhidai, L. Monitoring of the effect of oligotuftsin derivatives on the adhesion of crevicular fluid cells. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Lajkó, E., Mércz, K., Manea, M., Mező, G., Kőhidai, L., Pállinger, É. Cell adhesion and proliferation of BeWo choriocarcinoma cell line induced by GnRH-III based targeted systems. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Bäcker, H., Polgár, L., Soós, P., Lajkó, E., Láng, O., Weymann, A., Szabó, G., Kőhidai, L. Effect of heart scaffold ECM proteins on cell adhesion of cardiac myocytes - Model experiments of cell adhesion based loading of porcine heart scaffold. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)   

 

    Lajkó, E., Polgár, L., Leurs, U., Manea, M., Szabó, I., Mező, G., Kőhidai, L. Significance of cell adhesion and chemotaxis in therapeutic targeting of tumor cell lines by cytotoxic GnRH-III conjugates. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)


    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Impedimetry – Novel method for measurement of platelet adhesion. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)


   

 

 

 

 
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