Chemotaxis Research Group

Department of Genetics, Cell and Immunobiology

Semmelweis University

Nagyvárad tér 4., Budapest, Hungary 1089

 

News

  

Chemotaxis Workshop 2017

Theoretical Building (NET)

Semmelweis University

Budapest, Hungary

June 6 - 2017

Contact: kohlasz2@gmail.com

Program


IBCA 2013 materials in Archives   


 

Recent publications (2011-2017):

2017

Henrik Bäcker H, Polgár L, Soós P, Lajkó E, Láng O, Merkely B, Szabó G, Dohmen PM, Weymann A, Kőhidai L. Impedimetric analysis of the effect of decellularized porcine heart scaffold on human fibrosarcoma, endothelial, and cardiomyocyte cell lines. Med Sci Monitor 23: 2232-2240 /2017/

Sebestyén M, Szabó R, Kőhidai L, Pállinger É, Mező G, Kóczán Gy, Hudecz F. Synthesis, conformation and cytotoxicity of new, branched polymeric polypeptides containing hydrophobic amino acid or arginine moiety. Struct Chem. 28: 527-535 /2017/

2015 - 2016

Kőhidai L. Chemotaxis as an expression of communication of Tetrahymena. In: Biocommunication of ciliates. Ed: Witzany G. Springer pp. 65-82 /2016/

Lajkó E, Bányai P, Zámbó Zs, Krusinszki L, Szőke É, Kőhidai L. Targeted tumor therapy by Rubia tinctorum L.: analytical characterization of hydroxyanthraquinones and investigation of their selective cytotoxic, adhesion and migration modulator effects on melanoma cell lines (A2058 and HT168-M1). Cancer Cell Internat. 15:119 /2015/

Biri B, Kiss B, Király R, Schlosser G, Láng O, Kőhidai L, Fésüs L, Nyitray L. Metastasis-associated S100A4 is a specific amine donor and an activity-independent binding partner of transglutaminase-2. Biochemical J. 473:31-42 /2016/

Kőhidai L, Tóth K, Samotik P, Ranganathan K, Láng O, Tóth M, Ruskoaho H. Effect of vasoactive peptides in Tetrahymena - Chemotactic activities of adrenomedullin, proadrenomedullin N-terminal 20 peptide (PAMP) and calcitonin gene-related peptide (CGRP). Mol. Cell. Biochem. DOI :10.1007/s11010-015-2589-6 /2015/ (online version)

Diaz E, Zacarias AK, Pérez S, Vanegas O, Köhidai L, Padrón-Nieves M, Ponte-Sucre A. Effect of aliphatic, monocarboxylic, dicarboxylic, heterocyclic and sulphur-containing amino acids on Leishmania spp. chemotaxis. Parasitology 23:1-10 /2015/

Szemes Á, Lajkó E, Láng O, Kőhidai L. Chemotactic effect of mono- and disaccharides on the unicellular Tetrahymena pyriformis. Carbohydrate Research 407:158-165/2015/

Enyedi KN, Czajlik A, Knapp K, Láng A, Majer Z, Lajkó E, Kőhidai L, Perczel A, Mező G. Development of Cyclic NGR Peptides with Thioether Linkage: Structure and Dynamics Determining Deamidation and Bioactivity. J Med Chem. - Epub ahead of print /2015/

Muto Y, Guindon S, Umemura T, Kőhidai L, Ueda H. Adaptive evolution of formyl Peptide receptors in mammals. J Mol Evol. 80:130-141 /2015/

Szabó, R., Láng, O., Láng, J., Illyés, E., Kőhidai, L. Hudecz, F. Effect of SXWS/WSXWS peptides on chemotaxis and adhesion of the macrophage-like cell line J774. J Mol Recogn. doi: 10.1002/jmr.2439 /2015/

2014

Kuo CH, Láng J, Láng O, Kőhidai L, Sivaniah E. The facile generation of two-dimensional stiffness maps in durotactic cell platforms through thickness projections of three-dimensional submerged topography. Methods Cell Biol. 121:49-60 /2014/

2013

Arany E, Láng J, Somogyvári D, Láng O, Alapi T, Ilisz I, Gajda-Schrantz K, Dombi A, Kőhidai L, Hernádi K. Vacuum ultraviolet photolysis of diclofenac and the effects of its treated aqueous solutions on the proliferation and migratory responses of Tetrahymena pyriformis.Sci Total Environ. 468-469C, 996-1006 /2013/

Díaz E, Köhidai L, Ríos A, Vanegas O, Silva A, Szabó R, Mező G, Hudecz F, Ponte-Sucre A. Leishmania braziliensis: Cytotoxic, cytostatic and chemotactic effects of poly-lysine-methotrexate-conjugates.Exp Parasitol. 135, 134-141 /2013/

 

Lajkó E, Szabó I, Andódy K, Pungor A, Mező G, Kőhidai L. Investigation on chemotactic drug targeting (chemotaxis and adhesion) inducer effect of GnRH-III derivatives in Tetrahymena and human leukemia cell line.J Pept Sci. 19, 46-58 /2013/

2012

Kőhidai, L., Lajkó, E., Pállinger, É., Csaba, G. Verification of epigenetic inheritance in a unicellular model system. Multigenerational effects of hormonal imprinting. Cell Biol. Int. 36, 951–959  /2012/

 

Lang, J., Kohidai, L. Effects of the aquatic contaminant human pharmaceuticals and their mixtures on the proliferation and migratory responses of the bioindicator freshwater ciliate Tetrahymena. Chemosphere 89,592–601 /2012/

Kohidai, L. Tetrahymena pyriformis in motion. In: Microbiorobotics - Biologically Inspired Microscale Robotic Systems. Eds. Kim, MJ, Steager, E., Agung, AJ. Elsevier, pp 55-84 /2012/ 

Leurs, U., Lajkó, E.,Mező, G., Orbán, E.,  Öhlschläger, C.P., Marquardt, A., Kőhidai, L., Manea, M. GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate. Eur. J. Med. Chem. 52, 173-183 /2012/

Láng, O., Illyés, E., Menyhárd D.K., Láng, J., Sebestyén, F., Hudecz, F., Kőhidai, L. Chemotaxis induced by SXWS tetrapeptides in Tetrahymena—overlapping chemotactic effects of SXWS sequences and their identical amino acids. J. Mol. Recogn. 25, 24-31 /2012/

Lajkó, E. Polgár, L., Lengyel, J., Láng, O., Kőhidai, L., Magyar, K. Basic cell physiological activities (cell adhesion, chemotaxis, proliferation) induced by selegiline and its derivatives in Mono Mac 6 human monocytes. J. Neural Transm 119, 545-556 /2012/

2011

Láng, J., Rákász, V., Magyar, A., Pállinger, É., Kőhidai, L. Chemotactic effect of odorants and tastants on the ciliate Tetrahymena pyriformis. J. Rec. Sign. Transd. 31, 423-433 /2011/

Sáfár, O., Kőhidai, L., Hegedűs, A. Time-delayed model of unibased movement of Tetrahymena pyriformis. Period. Math. Hung. 63, 215-225 /2011/

Díaz, E., Köhidai, L., Ríos, A., Vanegas, O., Ponte-Sucre, A. Chemotaxis assays in vitro in Leishmania sp. evaluation of the capillary-two chambers technique in promastigotes. Rev. Facult. Farm. 74, 31-39 /2011/

 

Book chapters:

Abdallah, M.W., Michel, T., Kohidai, L. Autism spectrum disorders and circulating chemokines. In: The Comprehensive Guide to Autism, Eds. Patel, VB, Preedy, VR., Martin, CR; Springer; pp 1627-1642 /2014/

Kőhidai L, Lajkó E, Szabó I, Polgár I, Manea M, Mező G. GnRH-based drug targeting: Cell adhesion and migration modulator effects of GnRH derivatives in tumor cells. In: Gonadotropin-releasing hormone (GnRH): Production, structure and functions. Ed. Sills ES; Nova Publ. pp. 254-272 /2013/ 

Kőhidai, L. MIGRATION OF IMMUNE COMPETENT CELLS, HOMING AND EXTRAVASATION IN INFLAMMATION. In: Seminars in Immunology. Ed. Fülöp, K.; Semmelweis University, Budapest; pp. 133-150 (2012)  ISBN 978-963-9129-82-5
 
Kőhidai, L. DIE HOMING, DIE GEZIELTE MIGRATION VON IMMUNZELLEN. EXTRAVASATION IN ENTZÜNDUNGEN. Immunologie Seminare. Ed. Pap, E.; Semmelweis Universität, Budapest; pp. 148-162 (2012)  ISBN 978-963-9129-83-2

Kőhidai, L. AZ IMMUNSEJTEK MIGRÁCIÓJA, HOMING ÉS GYULLADÁSOS EXTRAVAZÁCIÓ. In: Immunológiai szemináriumok. Ed. Fülöp, K.;Semmelweis Egyetem, Budapest; pp. 130-148 (2012) ISBN 978-963-9129-81-8

 

Recent oral presentations:

   

    Kőhidai, L. Chemotaxome - A new member with complex biological entities in systems biology.(158th iCeMS Seminar - iCeMS - Kyoto University, Kyoto, 2014)

    Kőhidai, L. Chemotaxome – A new member with complex biological entities in systems biology. (BSS Formal Seminar, Cavendish Laboratory, University of Cambridge, 2013.)

    Kőhidai, L. ECIS Migration (ECIS Tutorial on Impedance-Based Cellular Assays, Budapest, 2013.)

    Kőhidai, L., Láng, O., Lajkó, E., Láng, J., Polgár, L., Mező, G. Impedimetry assays – Dedicated ways to evaluate migratory behavior of cells (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Láng, O., Nagy, K., Láng, J., Perczel-Kovách, K., Varga, G., Kőhidai, L. Monitoring dental stem cells on self-assembling peptide hydrogel scaffold by impedance based techniques. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Lajkó, E., Bányai, P., Zámbó, Zs., Szőke, É., Kőhidai, L. Natural cancer therapeutics – The effects of anthraquinones derived from Rubia tinctorum L. on melanoma cell lines. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Kosztin, A., Polgár, L., Kőhidai, L., Földes, G. Angiogenic effect of human pluripotent stem cell-derived endothelial cells. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Measurement of platelet function with impedimetry - The effect of agonists and heparin on adhesion and spreading of human platelets. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.

    Kőhidai, L., Lajkó, E, Láng, J., Láng, O., Vizi, T., Csaba, G., Pállinger, É. Apoptotic and anti-apoptotic effects of prenatal drugs in BeWo human trophoblast cells. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)

   

 

    Recent poster presentations:

 



    Lajkó, E., Bányai, P., Zámbó, Zs., Szőke, É., Kőhidai, L. Natural cancer therapeutics – The effects of anthraquinones derived from Rubia tinctorum L. on melanoma cell lines. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Kosztin, A., Polgár, L., Kőhidai, L., Földes, G. Angiogenic effect of human pluripotent stem cell-derived endothelial cells. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Measurement of platelet function with impedimetry - The effect of agonists and heparin on adhesion and spreading of human platelets. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Biri, B., Láng, O., Méhes, E., Czirók, A., Kőhidai, L., Nyitray, L. Motility and adhesion assays related to the effect of metastasis-associated S100A4 protein. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Láng, J., Kuo, R., Láng, O., Kőhidai, L., Sivaniah, E. Study of the interdependence of cell adhesion migration and mechanosensing using a complex, innovative approach. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Slezák, S., Lajkó, E., Pállinger, É., Bai, K.B., Mező, G., Gera, I., Kőhidai, L. Monitoring of the effect of oligotuftsin derivatives on the adhesion of crevicular fluid cells. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Lajkó, E., Mércz, K., Manea, M., Mező, G., Kőhidai, L., Pállinger, É. Cell adhesion and proliferation of BeWo choriocarcinoma cell line induced by GnRH-III based targeted systems. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)

    Bäcker, H., Polgár, L., Soós, P., Lajkó, E., Láng, O., Weymann, A., Szabó, G., Kőhidai, L. Effect of heart scaffold ECM proteins on cell adhesion of cardiac myocytes - Model experiments of cell adhesion based loading of porcine heart scaffold. (2nd Conference on Impedance-Based Cellular Assays - IBCA2013, Budapest, 2013.)   

 

    Lajkó, E., Polgár, L., Leurs, U., Manea, M., Szabó, I., Mező, G., Kőhidai, L. Significance of cell adhesion and chemotaxis in therapeutic targeting of tumor cell lines by cytotoxic GnRH-III conjugates. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)


    Polgár, L., Soós, P., Lajkó, E., Láng, O., Merkely, B., Kőhidai, L. Impedimetry – Novel method for measurement of platelet adhesion. (xCELLigence System - Global User Conference 2012, Stockholm, 2012.)


   

 

 

 

 
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